What Are Common Histological Features of Immune-Mediated Damage?
Histologically, immune-mediated damage is characterized by infiltration of inflammatory cells such as lymphocytes, macrophages, and plasma cells. You may also observe tissue necrosis, fibrosis, and the presence of autoantibodies within affected tissues. In autoimmune diseases, specific patterns of tissue damage can be identified, such as glomerulonephritis in lupus or synovitis in rheumatoid arthritis.
