What are Common Histological Features of Alzheimer's Disease?
Alzheimer's disease is characterized by the presence of amyloid plaques and neurofibrillary tangles. Amyloid plaques are extracellular deposits primarily composed of amyloid-beta protein. Neurofibrillary tangles are intracellular aggregates of hyperphosphorylated tau protein. These histological features are typically found in the hippocampus and other regions of the cerebral cortex.