Proper Fixation Using appropriate fixation methods is critical. Fixatives like formalin preserve tissue morphology by stabilizing proteins and preventing autolysis. It's essential to follow standardized protocols for fixation, including the correct concentration and exposure time, to ensure optimal tissue preservation.
Quality Reagents Employing high-quality reagents can significantly reduce the likelihood of resistance. Reagents should be fresh and stored under recommended conditions. Regularly check expiration dates and replace outdated chemicals to maintain their efficacy.
Controlled Environment Environmental factors such as temperature, humidity, and light exposure can impact tissue quality. Tissues should be stored in controlled environments to minimize degradation. Using cryopreservation techniques can also help maintain tissue integrity over time.
