1. Improved Techniques: Utilize advanced histological techniques such as immunohistochemistry and molecular pathology to extract maximum information from limited tissue. 2. Multiple Sections: Prepare multiple sections from the small sample to increase the likelihood of capturing relevant pathological features. 3. Quality Control: Ensure meticulous handling and processing of small samples to minimize artifacts and preserve tissue integrity. 4. Complementary Methods: Use complementary diagnostic methods like imaging techniques to provide additional context and information.
