Several strategies can be employed to mitigate biological interference:
- Proper Fixation: Choosing the right fixative and fixation time to minimize artifacts. - Special Stains: Using specific stains to differentiate between endogenous pigments and target cellular components. - Bleaching: Applying bleaching agents to reduce the visibility of interfering pigments. - Stringent Protocols: Following strict protocols for sample handling and preparation to avoid contamination and artifacts.