What histological changes occur in fungal infections?
Fungal infections often lead to the formation of granulomas, which are organized collections of immune cells aimed at containing the infection. Gomori methenamine silver (GMS) and Periodic Acid-Schiff (PAS) stains are commonly used to visualize fungal elements. Hyphae, spores, and yeast forms can be identified within the tissue, and there may be a mixed inflammatory response involving neutrophils, macrophages, and lymphocytes.
