- Use of Monoclonal Antibodies: These antibodies are more specific compared to polyclonal antibodies. - Epitope Mapping: Identifying the specific epitope that an antibody binds to can help in selecting antibodies with minimal cross reactivity. - Rigorous Validation: Testing antibodies in multiple systems and under various conditions to confirm specificity. - Antibody Purification: Affinity purification can help in isolating the most specific antibodies from a polyclonal mixture.
