Selecting the right staining techniques is fundamental to sequence selection. Common stains like Hematoxylin and Eosin (H&E) are often used for general tissue structure, while special stains like Periodic Acid-Schiff (PAS) or Masson's Trichrome are employed for specific components such as carbohydrates or connective tissue, respectively. Immunohistochemistry (IHC) and in situ hybridization (ISH) are chosen for detecting specific proteins and nucleic acids.