Histological studies of UCP1 involve a variety of techniques to visualize and quantify its expression. Immunohistochemistry (IHC) is commonly used to detect UCP1 in tissue sections by using specific antibodies that bind to the protein. This is often coupled with staining methods to highlight the presence of UCP1 in brown adipocytes. Additionally, electron microscopy can be used to observe the ultrastructure of mitochondria in BAT, providing insights into the density and distribution of UCP1.
