1. Fixation: Preserves tissue morphology and prevents degradation, typically using formalin. 2. Embedding: Involves infiltrating the tissue with paraffin wax to provide support for thin sectioning. 3. Sectioning: Thin slices of tissue are cut using a microtome. 4. Staining: Commonly, Hematoxylin and Eosin (H&E) stain is used to differentiate cellular components.