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intrinsic pathway of apoptosis
How is the Intrinsic Pathway Activated?
The process begins with the activation of pro-apoptotic members of the Bcl-2 family, such as
Bax
and
Bak
. These proteins cause mitochondrial outer membrane permeabilization (MOMP), leading to the release of cytochrome c into the cytosol.
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What is the Intrinsic Pathway of Apoptosis?
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