How Is the Presence of Exogenous Substances Detected in Tissues?
Detecting exogenous substances in tissues involves a variety of histological techniques:
Staining: Specific stains can highlight exogenous particles or their effects on tissues. For example, Prussian blue stain is used to detect iron deposits. Microscopy: Light and electron microscopy can reveal the presence and localization of foreign substances within cells and tissues. Immunohistochemistry: Uses antibodies to detect specific proteins associated with exogenous agents. Molecular Techniques: PCR and in situ hybridization can identify genetic material from infectious agents.
