For histological applications, PNA is typically labeled with a detectable marker. Common labels include fluorescent dyes such as FITC (Fluorescein isothiocyanate) for fluorescence microscopy, enzymes like HRP (Horseradish peroxidase) for immunohistochemistry, and biotin for streptavidin-based detection systems. The choice of label depends on the detection method and the specific requirements of the experiment.