To overcome its limitations, PLA can be modified in several ways: 1. Blending: PLA can be blended with other polymers, such as polyethylene glycol (PEG) or polyglycolic acid (PGA), to improve its mechanical properties and degradation rate. 2. Surface Modification: Techniques such as plasma treatment, chemical etching, and coating with proteins or peptides can enhance PLA’s surface properties, promoting better cell adhesion and proliferation. 3. Copolymerization: Creating copolymers of PLA with other monomers can tailor its properties to specific applications.