How is O-Linked Glycosylation Studied in Histology?
Histological techniques such as immunohistochemistry and lectin histochemistry are commonly used to study O-linked glycosylation. These methods involve using specific antibodies or lectins that bind to glycosylated proteins, allowing for their visualization under a microscope. Advances in mass spectrometry and glycomic profiling have also enhanced our understanding of this complex modification.
