hippocampal dentate gyrus

How is Neurogenesis in the Dentate Gyrus Studied?

Neurogenesis in the dentate gyrus can be studied through various histological techniques, such as:
- BrdU Labeling: Incorporation of BrdU (Bromodeoxyuridine) into the DNA of dividing cells allows for the identification of newly generated neurons.
- Immunohistochemistry: Specific markers like doublecortin (DCX) and Ki-67 can be used to identify immature neurons and proliferating cells, respectively.
- Confocal Microscopy: Provides high-resolution images to visualize the structure and spatial relationships of newly formed neurons.

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