Neurogenesis in the dentate gyrus can be studied through various histological techniques, such as:
- BrdU Labeling: Incorporation of BrdU (Bromodeoxyuridine) into the DNA of dividing cells allows for the identification of newly generated neurons. - Immunohistochemistry: Specific markers like doublecortin (DCX) and Ki-67 can be used to identify immature neurons and proliferating cells, respectively. - Confocal Microscopy: Provides high-resolution images to visualize the structure and spatial relationships of newly formed neurons.