How is Myocardial Stiffness Measured Histologically?
Histological assessment of myocardial stiffness involves various techniques:
Histopathology: Examining tissue sections stained with hematoxylin and eosin (H&E) or special stains like Masson's trichrome to assess collagen deposition. Immunohistochemistry: Using antibodies to detect specific proteins involved in fibrosis and inflammation. Electron Microscopy: Providing detailed images of ECM structure and cardiomyocyte ultrastructure.
