Detection of MUM1 in histological samples is typically performed using immunohistochemistry (IHC). This technique involves the use of specific antibodies that bind to the MUM1 protein, allowing for its visualization under a microscope. IHC staining for MUM1 is commonly used in the diagnosis and classification of lymphomas and other hematological malignancies. The presence and pattern of MUM1 staining can provide valuable information about the type and stage of the disease.