Histological techniques are essential for identifying and understanding loss of function at the cellular level. Some common methods include:
Staining Techniques: Special stains, such as hematoxylin and eosin (H&E), are used to highlight cellular structures and abnormalities. Microscopy: Light and electron microscopes allow for detailed visualization of cellular and subcellular structures. Immunohistochemistry: This technique uses antibodies to detect specific proteins, helping to identify dysfunctional cells. In Situ Hybridization: This method detects specific nucleic acid sequences, aiding in the identification of genetic mutations.
