How is Complement Activation Detected in Histology?
Complement activation in histological samples can be detected using various methods:
Immunohistochemistry (IHC): This technique involves the use of antibodies specific to complement proteins, allowing for their localization within tissue sections. Fluorescence Microscopy: Complement proteins can be tagged with fluorescent markers, enabling visualization under a fluorescence microscope. Enzyme-Linked Immunosorbent Assay (ELISA): While not a histological technique per se, ELISA can be used to quantify complement proteins in tissue extracts.
