How is Glomerulonephritis Identified Histologically?
Glomerulonephritis is identified by examining the glomeruli under the microscope. Key histological features include: - Hypercellularity: Increased number of cells within the glomerulus due to proliferation of endothelial and mesangial cells, as well as leukocyte infiltration. - Capillary Wall Thickening: This may occur due to immune complex deposition or basement membrane thickening. - Crescents: Formed by the proliferation of parietal epithelial cells and infiltration of monocytes and macrophages in severe cases.
