How is Fibroblast Proliferation Studied in Histology?
Histological techniques are essential for studying fibroblast proliferation. Tissue samples can be stained with specific markers to identify fibroblasts and assess their proliferation rate. Immunohistochemistry can be used to detect proliferation markers such as Ki-67 and PCNA, which are expressed in dividing cells. Additionally, techniques like in situ hybridization can help visualize gene expression patterns associated with fibroblast activity.