How is Chronic Liver Disease Diagnosed Histologically?
Diagnosis of chronic liver disease often involves a liver biopsy, where a small sample of liver tissue is examined under a microscope. Key histological techniques include:
Hematoxylin and Eosin (H&E) Staining: Provides a general overview of liver architecture and cellular details. Masson's Trichrome Stain: Specifically highlights fibrotic tissue, aiding in the assessment of fibrosis severity. Immunohistochemistry: Uses antibodies to detect specific antigens in liver tissue, useful for identifying viral infections and inflammatory markers.
