The detection of Candida in histological samples usually involves a combination of routine Hematoxylin and Eosin (H&E) staining and special fungal stains. In H&E-stained sections, Candida may be difficult to distinguish due to the presence of other cellular debris and microorganisms. Therefore, PAS and GMS stains are employed to provide a more definitive identification. These stains highlight the fungal cell walls, making Candida easier to detect against the background tissue.
