biopsy procedures

How is a Biopsy Processed in Histology?

Once a biopsy sample is collected, it undergoes several processing steps before being examined under a microscope:
Fixation: The tissue is preserved using chemical fixatives, such as formalin, to prevent degradation.
Embedding: The fixed tissue is embedded in a solid medium, usually paraffin wax, to provide support for sectioning.
Sectioning: Thin slices of the embedded tissue are cut using a microtome.
Staining: The tissue sections are stained with dyes to highlight various cellular components. Common stains include Hematoxylin and Eosin (H&E).
Microscopic Examination: The stained sections are examined under a microscope by a pathologist to identify any abnormalities.

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