Several issues can arise during tissue submission, including:
Poor Fixation: Inadequate fixation can lead to tissue degradation, making it difficult to interpret histological features. Artifacts: These are artificial changes introduced during tissue processing, such as folds, tears, or bubbles, which can obscure the tissue's true structure. Improper Sectioning: Sections that are too thick or too thin can affect the clarity and detail of the microscopic image. Inadequate Staining: Poor staining can make it challenging to differentiate between different tissue components.