How Does Tissue Clearing Enhance Deep Tissue Imaging?
Tissue clearing is a process that makes tissues transparent, allowing light to penetrate deeper. This is achieved by removing lipids and other scattering components. Techniques such as CLARITY, CUBIC, and iDISCO are commonly used for tissue clearing. Once cleared, tissues can be more effectively imaged using the aforementioned microscopy techniques, providing clearer and more detailed views of cellular structures.