How Does the Tumor Microenvironment Influence Aggressiveness?
The tumor microenvironment, including the surrounding stromal cells, blood vessels, and immune cells, plays a significant role in tumor growth and metastasis. Interactions between the tumor cells and the microenvironment can enhance tumor aggressiveness. For example, angiogenesis, the formation of new blood vessels, can supply the tumor with nutrients and oxygen, facilitating its growth and spread.