How does the Microenvironment Influence Cellular Behavior?
The microenvironment plays a crucial role in determining how cells behave, differentiate, and respond to stimuli. It influences:
Cell Proliferation: Growth factors within the microenvironment can stimulate or inhibit cell division. Cell Differentiation: The composition of the ECM and local signaling molecules can direct stem cells to become specific cell types. Cell Migration: Chemokines and ECM components can guide the movement of cells, which is essential during processes such as wound healing. Apoptosis: Signals within the microenvironment can trigger programmed cell death, maintaining tissue homeostasis.
