How Does Streptococcus Pyogenes Cause Tissue Damage?
Streptococcus pyogenes produces a variety of virulence factors that contribute to tissue damage. Among these are streptolysins, which are cytotoxic and can lead to cell lysis. The bacterium also secretes hyaluronidase, an enzyme that degrades connective tissue, facilitating the spread of infection. These virulence factors not only damage the host tissue but also trigger a robust immune response that can exacerbate tissue injury.
