Several histological stains are employed to identify and study Streptococcus pyogenes in tissue samples. The Gram stain is essential for identifying the Gram-positive cocci. Other stains like Hematoxylin and Eosin (H&E) are used to examine tissue architecture and the inflammatory response. Special stains such as Giemsa or Periodic Acid-Schiff (PAS) may also be utilized to highlight specific components like bacterial capsules or polysaccharides.
