As individuals age, several changes occur in the spongiosa:
Density Reduction: The trabeculae become thinner and less dense, which can lead to conditions like osteoporosis. Marrow Composition: Red bone marrow is gradually replaced by yellow bone marrow, reducing the bone’s hematopoietic capacity. Remodeling Rate: The balance between bone formation and resorption shifts, often resulting in a net loss of bone tissue.