How Does Precipitate Formation Affect Histological Stains?
Precipitates can interfere with the staining process in several ways:
1. Masking of Tissue Details: Precipitates can obscure cellular structures, making it difficult to interpret the tissue morphology. 2. Non-Specific Binding: Some precipitates may bind non-specifically to tissues, leading to background staining and false-positive results. 3. Reduced Penetration: Precipitates can block the penetration of stains into the tissue, resulting in uneven staining.