In the context of histology, immunotherapy involves understanding the interaction between the immune system and cancer cells at a microscopic level. Immunohistochemistry (IHC) is a key technique used to visualize the expression of immune markers on tissue sections. By staining tissues with antibodies specific to immune cell markers, pathologists can assess the infiltration of immune cells within the tumor microenvironment. This information is crucial for determining the potential efficacy of immunotherapy treatments.