Immune cell infiltration involves a series of steps including chemotaxis, adhesion, and transmigration. Chemotaxis is the directed movement of cells towards chemical attractants released by infected or damaged tissues. Adhesion involves the binding of immune cells to endothelial cells lining the blood vessels, mediated by adhesion molecules like selectins and integrins. Finally, transmigration, or diapedesis, is the process by which immune cells pass through the endothelial barrier to enter the tissue.
