Histology scanners use advanced optics and cameras to capture high-resolution images of tissue sections mounted on glass slides. Here’s a brief overview of the process:
Slide Loading: Glass slides are loaded into the scanner, either manually or through an automated loader. Image Capture: The scanner uses a combination of brightfield or fluorescence microscopy to capture images. The tissue section is illuminated, and images are captured at multiple focal planes to ensure sharpness. Stitching: If the tissue section is large, the scanner captures multiple overlapping images and stitches them together to create a seamless high-resolution image. Storage: The digital images are stored in various formats, such as JPEG, TIFF, or specialized formats like SVS (Slide Viewing Software). These images can then be viewed and analyzed using specialized software.