Histological techniques are indispensable for diagnosing neurodegenerative diseases. Common methods include:
Immunohistochemistry: This technique uses antibodies to detect specific proteins within tissue sections, aiding in the identification of pathological protein aggregates. Hematoxylin and Eosin (H&E) staining: This basic staining method provides an overview of tissue structure and highlights cellular and extracellular components. Silver staining: Used to visualize neurofibrillary tangles and amyloid plaques in Alzheimer’s disease.