How do Gram-Positive Bacteria Differ from Gram-Negative Bacteria?
The primary differences between gram-positive and gram-negative bacteria lie in their cell wall composition and the outcome of the Gram staining process: - Cell Wall Structure: Gram-positive bacteria have a thick peptidoglycan layer, while gram-negative bacteria have a thin peptidoglycan layer surrounded by an outer membrane containing lipopolysaccharides. - Gram Staining: Gram-positive bacteria retain the crystal violet stain, appearing violet, whereas gram-negative bacteria do not, appearing pink/red after counterstaining. - Response to Antibiotics: Gram-positive bacteria are typically more susceptible to antibiotics that target cell wall synthesis, like penicillin.
