How Do Enteroendocrine Cells Adapt to Changes in Diet?
Enteroendocrine cells exhibit plasticity and can adapt to changes in diet. For instance, a high-fat diet may increase the number of CCK-producing cells to enhance lipid digestion. Conversely, fasting or caloric restriction can alter the secretion of hormones like GLP-1 to modulate energy expenditure and glucose metabolism. This adaptive ability underscores the dynamic nature of enteroendocrine cells in response to nutritional cues.
