What Techniques Are Used to Study Genomics in Histology?
Several advanced techniques are employed to study genomics within the context of histology:
In situ hybridization (ISH): This technique localizes specific nucleic acid targets within fixed tissues and cells, allowing visualization of gene expression patterns. Immunohistochemistry (IHC): Though primarily used to detect proteins, IHC can be combined with genomic data to study gene expression at the protein level. RNA sequencing (RNA-seq): This technique analyzes the entire transcriptome, providing insights into gene expression profiles in different tissues. CRISPR-Cas9: A genome editing tool that can be used to investigate the role of specific genes in tissue development and disease.
