How Can Histology Help in Understanding Inflammation?
Histological techniques allow for the detailed examination of synovial tissue, helping to identify changes at the cellular level. By using staining methods such as Hematoxylin and Eosin (H&E), scientists can visualize the infiltration of immune cells, synovial membrane thickening, and angiogenesis. Immunohistochemistry further aids in identifying specific markers of inflammation like TNF-alpha and IL-1, providing insights into the molecular pathways involved.
