Several techniques are employed to fabricate scaffolds, each with its advantages and limitations.
Electrospinning: This technique produces fibrous scaffolds with high porosity, mimicking the natural ECM. It is suitable for creating nanofibers that enhance cell adhesion and proliferation. 3D Printing: Also known as additive manufacturing, 3D printing allows for precise control over scaffold architecture. It enables the creation of complex and patient-specific structures. Solvent Casting/Particulate Leaching: This method involves dissolving a polymer in a solvent, casting it into a mold, and leaching out the solvent to create a porous scaffold.