How are Pre-Cancerous Changes Detected Histologically?
Histologically, pre-cancerous conditions are identified by examining tissue samples under a microscope. Key changes include abnormal cell architecture, increased nuclear-to-cytoplasmic ratio, hyperchromasia, and atypical mitotic figures. Techniques such as Hematoxylin and Eosin (H&E) staining and immunohistochemistry are commonly employed to highlight these abnormalities.
