How are Plasma Cells Identified in Histological Samples?
Plasma cells can be identified using various staining techniques in histology. Hematoxylin and eosin (H&E) staining reveals their characteristic morphology. Immunohistochemical staining for specific markers such as CD138, CD38, and MUM1 can also be used to identify plasma cells. Additionally, in situ hybridization techniques may be employed to detect specific RNA sequences associated with plasma cells.