How are Pancreatic Stellate Cells Studied in Histology?
In histological studies, PSCs can be identified by their unique morphology and specific markers. Quiescent PSCs are characterized by their star-shaped appearance and the presence of lipid droplets, which can be visualized using oil red O staining. Activated PSCs express markers such as alpha-smooth muscle actin (α-SMA), vimentin, and desmin, which can be detected using immunohistochemistry (IHC).
