In histology, OPCs are studied using various techniques, including immunohistochemistry, in situ hybridization, and electron microscopy. Immunohistochemistry involves the use of antibodies to detect specific proteins expressed by OPCs, such as PDGFRA and NG2. In situ hybridization allows for the detection of mRNA transcripts specific to OPCs, providing insights into their gene expression profiles. Electron microscopy offers high-resolution images of OPCs and their interactions with other cells in the CNS.
