How are Neuroendocrine Granules Visualized in Histology?
In histology, neuroendocrine granules can be visualized using special staining techniques and microscopy methods. Immunohistochemistry is commonly used to detect specific proteins or peptides within the granules by using antibodies that bind to these molecules. Electron microscopy provides detailed images of the granules' ultrastructure, revealing their size, shape, and dense-core content. Additionally, fluorescence microscopy can be employed to visualize granules stained with fluorescent dyes or tagged with fluorescent proteins.
