How are Immune Suppressive Cells Identified in Histology?
Histological identification of immune suppressive cells typically involves immunohistochemical staining techniques. This method uses specific antibodies to detect the presence of cell surface markers or transcription factors unique to each type of immune suppressive cell. For example, Tregs are identified by staining for CD25 and FoxP3, while MDSCs are marked by CD11b and Gr-1, and TAMs by CD68 and CD163.
