How Are Histological Studies Integrated into Drug Development?

In drug development, histological studies are essential at various stages. During the preclinical phase, histological analysis of animal models helps in assessing the efficacy and safety of new drug candidates. By examining tissue samples, researchers can identify potential toxic effects and understand the drug’s mechanism of action at the cellular level. In clinical trials, histological evaluations of patient biopsies provide critical data on the drug’s impact on target tissues, guiding dose adjustments and therapeutic strategies.