genomic alterations

How are Genomic Alterations Detected?

Several techniques are used to detect genomic alterations:
1. Polymerase Chain Reaction (PCR): Amplifies specific DNA sequences, allowing for the detection of mutations.
2. Fluorescence In Situ Hybridization (FISH): Uses fluorescent probes to identify chromosomal abnormalities.
3. Next-Generation Sequencing (NGS): Provides comprehensive data on the entire genome, enabling the identification of various alterations.
4. Microarray Analysis: Detects CNVs and gene expression changes across the genome.

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